Network Inference

Network Portal

The Network Portal is a database of gene transcription regulatory networks and enables exploration, annotation and comparative analysis.

Deciphering the complexity of biological systems requires a systems-level view of regulatory players and their interactions. However, inference of these complex interactions is challenging, and further, visualizing and analyzing these interactions often requires advanced computational expertise, tools and resources.

Network Portal provides analysis and visualization tools for selected gene regulatory networks to aid researchers in biological discovery and hypothesis development. It provides a user-friendly interface, extensive search capabilities and a number of visualization tools. We are also constantly adding regulatory networks for new species. Increasing the number of network models will also enable comparative network biology. We are also developing tools for comparing network models and these will be integrated into the portal as soon as they are available.

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Reiss, David J., Nitin S. Baliga, and Richard Bonneau. “Integrated Biclustering of Heterogeneous Genome-Wide Datasets for the Inference of Global Regulatory Networks.” BMC Bioinformatics 7 (2006): 280. Cite
Turkarslan, Serdar, Elisabeth J. Wurtmann, Wei-Ju Wu, Ning Jiang, J. Christopher Bare, Karen Foley, David J. Reiss, Pavel Novichkov, and Nitin S. Baliga. “Network Portal: A Database for Storage, Analysis and Visualization of Biological  Networks.” Nucleic Acids Research 42, no. Database issue (January 2014): D184-190. Cite