The Baliga Lab develops predictive models to explain, predict and manipulate complex biological behaviors in order to catalyze strategies for personalized medicine, and a sustainable environment.

Interaction with the environment is central to how information within our DNA is decoded into observable phenotypes. Dr. Baliga and his laboratory are using a multidisciplinary systems approach to understand this process. Once delineated, the engineering principles governing assembly of biological systems will help unlock potentials within diverse organisms, and enable spectacular solutions for problems in environment and medicine.

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Baliga Lab researchers and collaborators found that genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma

ISB researchers Drs. Matt Wall, Serdar Turkarslan, Nitin Baliga, and others, along with collaborators, have developed a technology to generate a patient-specific disease-relevance network map to accurately predict risk, personalize therapies, and discover novel drug targets for solid and liquid tumors.

Genetic Switch May Predict Diatom Resilience in Acidified Oceans

Researchers from ISB’s Baliga Lab recently published a paper in the journal Frontiers in Marine Science, in which they identified a diatom-specific gene that may play a key role in predicting when diatoms might transition from a low/moderate to a high carbon dioxide environment.

ISB Researchers Among World-Class Experts Targeting Coral Bleaching

ISB Drs. Jacob Valenzuela and Nitin Baliga are working to answer key questions about how climate change is affecting marine life and food supplies. The Paul G. Allen Family Foundation announced a $4 million grant over three years to support efforts aimed to help coral reefs survive the impacts of climate change.

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