About ISB

ISB is a biological research facility located near the UW campus in Seattle, WA. Committed to the development of predictive, preventive medicine, ISB uses systems approaches to understand the biology and medicine. It is located in the fascinating city of Fremont with a long and interesting history and many interesting shops and locations. The facility is right next to the Burke-Gilman trail a beautiful biking and jogging trail that goes through various locations such a the UW campus and the Gas Works park.

The overarching goal of the ISB is to promote systems biology approaches to understand biology and to make medicine personalized, predictive and preventive. Systems Biology involves looking at a biological entity (perhaps a cell, a particular pathway or process, or a collection of genes) as a collection of parts, a system, that work together and observing their interactions rather than the parts. It is a unique approach that looks at the entire system at once. Using large scale technology and powerful computer algorithms, it reveals insights about how the building blocks of life work in the presence of others that cannot be revealed while studying them in isolation. ISB’s main medical goal is the development and advancement of predictive and preventive medicine.

As per its systems biology approach, ISB treats sickness as a malfunction in the system, parts that are not working. ISB aims to predict and prevent such malfunctions by fully understanding the healthy and sick systems and the signals produced by sick systems. Measuring changes in protein expression, gathering data from accurate computer models, and taking and analyzing the patients genome are current technologies and techniques being developed by the ISB in order to make their dream of predictive, preventive, and personalized medicine come true.

Baliga Lab