DegreeUniversity of Michigan: B.S. in Microbiology, 2002 Massachusetts Institute of Technology: M.S. in Environmental Engineering, 2005 Sep 2005-Apr 2007: Research Associate, Pfizer, Inc., Cambridge, MA Apr 2007-Aug 2008: Senior Research Associate, Amgen, Inc., Cambridge, MA Aug 2008-May 2013: Doctoral Candidate, UNC, Chapel Hill, NC University of North Carolina: Ph.D. in Biochemistry & Biophysics, 2013 June 2013-present: Postdoctoral Fellow, Institute for Systems Biology, Seattle, WA
Areas of Expertise
LinksMTB Network Portal
Fun/InterestFavorite Drink: Red wine Favorite Food: Cake with lots of frosting Favorite Book: Count of Monte Cristo Favorite Movie: What About Bob?
Regulatory Networks of Tuberculosis
Mycobacterium tuberculosis (MTB) is the bacterium that causes tuberculosis, a disease which kills one person every 30 seconds. Its success as a human pathogen is largely due to its ability to alter gene expression and adapt to the complex host environment within which it resides. Dr. Peterson works with scientists at ISB and Seattle Biomed to track gene expression in MTB by constructing a gene regulatory network model. Using the model, she can predict sets of genes that are similarly expressed, the proteins or factors that bind to DNA to influence their gene expression, and the environmental conditions in which these regulatory interactions occur. This global analysis gives us a clearer idea of MTB pathogenicity and, by engaging in a systems biology approach, we better understand how the pathogen responds to a diversity of stress conditions such as low oxygen conditions, host interactions, and unfavorable nutrient availability. Her model is now publicly available here: http://networks.systemsbiology.net/mtb/
Why I got into Science…
"Growing up, I was always interested in science and biology and the idea of becoming an expert in a field and making new discoveries. It wasn't until a neighbor moved in next door who worked at Pfizer R&D that I thought about scientific research as a career option. "