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News From Baliga Lab

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May 16, 2013 Recent Publication: A role for programmed cell death in the microbial loop

Our researchers discover that programmed cell death of algae may play an important role in driving the global carbon cycle

 

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January 23, 2013 Publication: Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis.

Here we report that during continuous culture of Methanococcus maripaludis under defined nutrient conditions, growth yields relative to methane production decreased markedly with either H(2) excess or formate excess.

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January 23, 2013 Publication: Metallochaperones Regulate Intracellular Copper Levels

This model accurately recapitulates known dynamical properties of the Cu circuit and predicts that intracellular Cu-buffering emerges as a consequence of the interplay of paralogous metallochaperones that traffic and allocate Cu to distinct targets.

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June 22, 2012 Nitin Baliga received an Award from NWABR

 Nitin Baliga received the 2012 Alvin J. Thompson Award from NWABR for his contributions to high school science education. He and two other award recipients were honored at an event on June 12.

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April 06, 2012 Mapping transcription factor binding sites

The Marc Facciotti lab at UC Davis published A workflow for genome-wide mapping of archaeal transcription factors with ChIP-seq. This paper demonstrates a novel ChIP-seq workflow for mapping genome-wide binding sites of natively expressed transcription factors in archaea. Gaggle software features prominently.

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February 29, 2012 Systems Bioinformatics Workshop 2012

The Systems Bioinformatics Workshop 2012 will be held at ISB on September 10th and 11th. Presentations and tutorials will cover the following topics:

  • network inference and analysis
  • scientific computing in the cloud
  • biological data visualization
  • software architecture for biological research
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February 07, 2012 Strange organisms shed light on how living things evolve

 

Seattle Local Health Guide Blog published an interview about our recent paper "Niche adaptation by expansion and...

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January 07, 2012 Genome Browser 1.0 Build 186 released

This release includes contributions from Diego Martinez Salvanha of the Vêncio lab at the University of Sao Paulo, Ribeirão Preto, Brazil and Kai Chen of Genomatica. Thanks to them!

gaggle.systemsbiology.net/docs/geese/genomebrowser

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November 23, 2011 Niche adaptation by expansion and reprogramming of general transcription factors

 

Experimental analysis of TFB family proteins in a halophilic archaeon reveals complex environment-dependent fitness contributions. Gene conversion events among these proteins can generate novel niche adaptation capabilities, a process that may have contributed to archaeal adaptation to extreme environments.

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July 15, 2011 GaggleBridge: collaborative data analysis

Florian Battke, Stephan Symons, Alexander Herbig and Kay Nieselt at the University of Tuebingen published a paper on their GaggleBridge software. GaggleBridge transparently extends Gaggle to allow data exchange between users at different geographic locations using network communication. GaggleBridge can automatically set up SSH tunnels to traverse firewalls while adding security features.

GaggleBridge is available as open-source software at http://it.inf.uni-tuebingen.de/gb.

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