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News From Baliga Lab

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April 06, 2012 Mapping transcription factor binding sites

The Marc Facciotti lab at UC Davis published A workflow for genome-wide mapping of archaeal transcription factors with ChIP-seq. This paper demonstrates a novel ChIP-seq workflow for mapping genome-wide binding sites of natively expressed transcription factors in archaea. Gaggle software features prominently.

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February 29, 2012 Systems Bioinformatics Workshop 2012

The Systems Bioinformatics Workshop 2012 will be held at ISB on September 10th and 11th. Presentations and tutorials will cover the following topics:

  • network inference and analysis
  • scientific computing in the cloud
  • biological data visualization
  • software architecture for biological research
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February 07, 2012 Strange organisms shed light on how living things evolve

 

Seattle Local Health Guide Blog published an interview about our recent paper "Niche adaptation by expansion and...

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January 07, 2012 Genome Browser 1.0 Build 186 released

This release includes contributions from Diego Martinez Salvanha of the Vêncio lab at the University of Sao Paulo, Ribeirão Preto, Brazil and Kai Chen of Genomatica. Thanks to them!

gaggle.systemsbiology.net/docs/geese/genomebrowser

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November 23, 2011 Niche adaptation by expansion and reprogramming of general transcription factors

 

Experimental analysis of TFB family proteins in a halophilic archaeon reveals complex environment-dependent fitness contributions. Gene conversion events among these proteins can generate novel niche adaptation capabilities, a process that may have contributed to archaeal adaptation to extreme environments.

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July 15, 2011 GaggleBridge: collaborative data analysis

Florian Battke, Stephan Symons, Alexander Herbig and Kay Nieselt at the University of Tuebingen published a paper on their GaggleBridge software. GaggleBridge transparently extends Gaggle to allow data exchange between users at different geographic locations using network communication. GaggleBridge can automatically set up SSH tunnels to traverse firewalls while adding security features.

GaggleBridge is available as open-source software at http://it.inf.uni-tuebingen.de/gb.

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June 13, 2011 The Gaggle Systems Bioinformatics Workshop 2011

The Institute for Systems Biology hosted a workshop focusing on interoperability between bioinformatics software tools, bringing together over 40 software developers and scientists for discussion and collaboration. The format was one day of talks, followed on the second day, by a hackathon, a forum for coding, discussion, informal presentations and collaboration.

Thanks to all who participated!

Visit the workshop site for more information.

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May 28, 2011 Gaggle-JSON prototype

A prototype implementation of Gaggle data types encoded in JSON is available at gaggle-json.systemsbiology.net. Additional prototyping of support for HTTP and JSON transport in the Gaggle Boss is available in Wei-ju Wu's Github repo.

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May 20, 2011 miRvestigator Framework is now published

miRvestigator is a web application to identify miRNAs responsible for co-regulated gene expression patterns discovered through transcriptome profiling.

miRvestigator was published in the Webserver issue of Nucleic Acid Research.

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May 09, 2011 The Big Science Challenge With Biofuel: A Chat with ISB’s Nitin Baliga

Talk to any biofuels entrepreneur, and you are likely to hear a passionate riff on why their technology trumps all the up-and-comers.

Some, like San Diego-based Sapphire Energy, say you’ve got to harness free sunlight and the magic of photosynthesis, to grow oil-rich algae in open ponds at the scale of modern agriculture.

 

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