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News From Baliga Lab

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June 29, 2009 A Taskmaster Transcription Factor

"Researchers showed that a single transcription factor in a tiny, salt-loving archaeon coordinates the expression of more than 100 newly-obtained genes."

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March 10, 2009 All Systems Go

On April 22. 2006. Nitin Ballga. a microbiologist at the Institute for Systems Biology in Seattle, was spending a lazy Saturday afternoon at home when he noticed an enticing email in his inbox from his ISB collaborator Richard Bonneau. The subject line: "woooooohoooooo!"

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March 01, 2009 A Whole New System

Founded in 2000 by well-known scientists who defected from their academic posts at the nearby University of Washington, the Institute for Systems Biology laid the groundwork for academic and for-profit organizations alike to buy into the nascent concept of large-scale biology.

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March 01, 2009 Systems Biology Weathers the Storm

Last December, in the face of one of the worst winter storms in decades, the Institute for Systems Biology declared a snow day. Most researchers stayed home, and a calm stillness transcended the Institute's three-story home overlooking Seattle's snow-crested Lake Union.

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October 18, 2008 The Data is Your Palette

Over at the Institute for Systems Biology, which hosts several visualization tools on its website, Nitin Baliga and his group recently added a tool to their database and software integration framework Gaggle.

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September 18, 2008 A New Computer Model Sheds Lights On The Complex Networks In A Cell

Turn on the radio, and a marvelous thing happens. Intricately wired circuits come to life and, as if by magic, the speakers send out music. Of course, you protest, it's not magic, as a quick look inside can show.

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March 01, 2008 A Predictive model for transcriptional control of physiology in a free living cell (Cell)

Our recent Cell publication (A Predictive model for transcriptional control of physiology in a free living cell) has been featured in a number of news articles.

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January 16, 2008 Meeting Systems Biology Data Demands

Open source software allows for integration and analysis of massive data sets

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December 18, 2007 Firegoose paper

The Firegoose paper ranked second-most viewed on BMC Bioinformatics website.

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July 26, 2007 Systems Biology and Sustainability

Right here in Seattle, at the Institute for Systems Biology, Dr. Nitin Baliga and his group are taking a systems level approach to understand how organisms respond to complex changes in their environment.

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May 17, 2007 With Repository Overload, Researchers try new ways to integrate

The problem is that there are many types, formats and dimensions of data, and, therefore as many or even more  types of software. Its a two-fold problem.

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May 06, 2007 Highlights from "Managing the Data Explosion in Systems Biology"

At the December 2006 American Society for Cell Biology meeting, there was a Special Interest Subgroup entitled "Managing the Data Explosion in Systems Biology".

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November 11, 2006 Weaving a tapestry in eScience

It seems clear to me that the key to building effective eScience environments is doing just what this Gaggle of bioinformatics researchers have done: stitch together small best-of-breed modules into a cohesive whole, rather than build a monolithic application.

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April 18, 2006 Most influential publications in high-throughput screening (Gaggle)

Gaggle manuscript ranked in the top 100 (#49) "Most influential publications in high-throughput screening" in 2006

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February 18, 2006 ISB Informatics: Systems Biology in action by Nat Goodman

In this review, I describe a sample of the software used at ISB, focusing on elements that have moved beyond proof-of-principle and may be relevant to other groups engaged in systems biology.

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November 11, 2004 Bionews

Completion of Haloarcula marismortui Genome sequencing
featured in Genome Research

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November 03, 2004 Completion of Haloarcula marismortui Genome Sequencing

Scientists at the Institute for Systems Biology (ISB) in collaboration with researchers from National Yan Ming University (NYMU) in Taiwan and University of Texas at Austin have fully sequenced the complete genome of Haloarcula marismortui, a microorganism that thrives in the Dead Sea.

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July 18, 2004 Systems Approach Depicts How Halobacterium Responds to Metal Fluxes

Systems Approach Depicts How Halobacterium Responds to Metal Fluxes

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